KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX3X
All Species:
23.64
Human Site:
S143
Identified Species:
37.14
UniProt:
O00571
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00571
NP_001347.3
662
73243
S143
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Chimpanzee
Pan troglodytes
Q6GVM6
660
73172
S141
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Rhesus Macaque
Macaca mulatta
XP_001095294
910
100218
S393
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Dog
Lupus familis
XP_861268
662
73195
S143
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62167
662
73083
S143
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Rat
Rattus norvegicus
NP_001102328
659
72976
S141
W
S
K
P
L
P
P
S
E
R
L
E
Q
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512924
651
71975
F137
D
R
L
E
Q
E
L
F
S
G
G
N
T
G
I
Chicken
Gallus gallus
NP_001025971
651
72031
E141
P
S
E
R
L
E
Q
E
L
F
S
G
S
N
T
Frog
Xenopus laevis
P24346
697
77284
N184
W
S
K
P
L
A
P
N
D
R
V
E
Q
E
L
Zebra Danio
Brachydanio rerio
NP_571016
688
75828
N171
W
S
K
P
L
P
P
N
E
R
L
E
H
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHP0
798
85063
D258
Y
T
K
L
G
A
R
D
E
R
L
E
V
E
L
Honey Bee
Apis mellifera
XP_391829
701
78642
D186
W
T
I
P
T
S
R
D
E
R
L
E
V
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2F9
646
69224
S137
E
D
I
P
I
E
T
S
G
D
N
V
P
P
P
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
I132
P
D
Y
H
S
S
G
I
K
F
D
N
Y
D
N
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
E157
A
N
P
R
V
E
R
E
L
F
G
T
P
D
D
Conservation
Percent
Protein Identity:
100
91.3
70.1
99.8
N.A.
98.6
95.3
N.A.
95.9
91.2
82.2
76.3
N.A.
51.7
58
N.A.
N.A.
Protein Similarity:
100
95.3
70.3
99.8
N.A.
99
97.1
N.A.
97.2
94.7
88
83.8
N.A.
63.4
70
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
73.3
86.6
N.A.
46.6
53.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
20
93.3
93.3
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.5
49.4
52
Protein Similarity:
N.A.
N.A.
N.A.
64.6
65.2
64.8
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
0
0
0
14
7
7
7
0
0
14
7
% D
% Glu:
7
0
7
7
0
27
0
14
60
0
0
67
0
67
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
20
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
7
0
7
7
14
7
0
7
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
14
0
7
0
0
7
0
0
0
0
0
0
7
% I
% Lys:
0
0
60
0
0
0
0
0
7
0
0
0
0
0
0
% K
% Leu:
0
0
7
7
60
0
7
0
14
0
60
0
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
14
0
0
7
14
0
7
7
% N
% Pro:
14
0
7
67
0
47
54
0
0
0
0
0
14
7
7
% P
% Gln:
0
0
0
0
7
0
7
0
0
0
0
0
47
0
0
% Q
% Arg:
0
7
0
14
0
0
20
0
0
67
0
0
0
0
0
% R
% Ser:
0
60
0
0
7
14
0
47
7
0
7
0
7
0
0
% S
% Thr:
0
14
0
0
7
0
7
0
0
0
0
7
7
0
7
% T
% Val:
0
0
0
0
7
0
0
0
0
0
7
7
14
0
0
% V
% Trp:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _